Announcement:

Our latest paper in collaboration with Pfizer on the role of OCT2/MATE in creatinine clearance is accepted in JPET.

Find out more

A man writing something in a notebook

Home › Resources › Articles and posters

Resources: Articles and posters

A Sensitive Nephrotoxicity Assay of in vitro Podocyte Effacement

Kathryn Garner, Ben Coker, Nick Brittain, Kirsten Ramsey, Kate Gilroy, Elena Tasinato

Significance of organic anion transporter 2 and organic cation transporter 2 in creatinine clearance: Mechanistic evaluation using freshly-prepared human primary renal proximal tubule cells

Sumathy Mathialagan, Git Chung, Keith Pye, A. David Rodrigues, Manthena V. S. Varma and Colin Brown

A Live Cell High Content Imaging Assay for Monitoring Large Molecules Uptake into aProximateTM Proximal Tubule Epithelial Cells via Megalin and Cubulin

Jonathon Lowe, Ben Coker, Keith Pye, Colin D.A. Brown, Kathryn Garner

Development of highly-differentiated human primary proximal tubule MPS model (aProximate MPS™ Flow)

Francesca Pisapia, Elena Tasinato, Kathryn Garner, and Colin Brown

The aProximate™ in vitro renal proximal tubule cell model as a platform to investigate the renal uptake and nephrotoxic liability of Antisense Oligonucleotide drug molecules

Colin D A Brown, Siannah Shuttleworth, Kathryn Garner, Jonathan Lowe, Keith Pye

An in-vitro high-content imaging assay for the study of fibroblast activation and matrix deposition

Fiona Leslie, Chloe Whiting, Megan Webster

Comparison of multiple batches of human iPSC-derived retinal organoids produced at large scale

Carolina Gándara, Will Atkin, Hannah Steward , Madalaine Kay , George Buchanan, Lyle Armstrong , Valeria Chichagova

the glomerulus

Developing a Comprehensive Biomarker Package for Detecting Drug-Induced Injury in Podocytes

Kate Gilroy, Jonathan Lowe, Jessica Ogden, Cindy Carr, Colin Brown, and Kathryn Garner

Albumin and siRNA Uptake by Megalin Cubulin.

The aProximate™ in vitro renal proximal tubule cell model as a platform to investigate the renal uptake & nephrotoxic liability of Antisense Oligonucleotide drug molecules

Colin D A Brown, Siannah Shuttleworth, Jonathan Lowe, Keith Pye