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A microscope image of a nephron model

Predictive In Vitro Models

Accelerate your drug discovery with predictive in vitro models designed to replicate human physiology. Contact us today to find the right model for your research.

At Newcells, we offer a portfolio of cutting-edge in vitro models developed from human iPSCs, tailored for preclinical screening, mechanistic studies, and translational research. Our predictive models are engineered to deliver physiologically relevant data, reducing reliance on animal models and improving clinical relevance.

Retinal Models

Our retinal organoids and RPE models closely mimic the structure and function of the human eye, enabling accurate assessment of drug efficacy and toxicity. These models are validated for light responsiveness, phagocytosis, and morphological fidelity.

Kidney Models

Recreate kidney nephron function in vitro with our human iPSC-derived proximal tubule and glomerular models. Designed for assessing nephrotoxicity and drug transport, these systems provide a reliable platform for renal safety and pharmacokinetics.

Lung Models

Advance your respiratory research with our small airway epithelial and FMT assays. Built on primary and iPSC-derived lung cells, these models replicate the lung epithelial barrier and are ideal for inhaled drug delivery, toxicity, and barrier function studies.

All models are rigorously validated and optimised for predictive power, enabling you to generate reliable, translatable data with greater speed and accuracy.

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Why Choose Us?

We enable the generation of robust and informative data to support critical decisions during any stage of drug-development.

1.

Our experts have validated and optimised our complex and functional tissue models for several applications within the drug development process, and inhalation drug assessment.

2.

Newcells builds in vitro models and services to de-risk and improve clinical translation and drug discovery, enabling better decision-making earlier in the development pipeline.

3.

We support key stages of your programme - using predictive, human-relevant models that offer greater translatability and reduce reliance on animal studies.

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About Newcells Biotech

Newcells Biotech provides clients with validated in vitro tools to understand how drugs interact with tissues. We enable the generation of robust and informative data to support critical decisions during any stage of drug-development.

We believe that improving the in vitro models available to drug discovery and development scientists is a key method for increasing the efficiency of in-vitro to in-vivo translation and ultimately to delivering new therapies to patients.

By applying our expertise in iPSCs, primary tissues, a deep understanding of cellular physiology and organoid technology, we have built validated models and assays that have proven to be predictive of how drugs interact with tissues and organs.

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Innovative company located in Newcastle upon Tyne, in the Northeast of England

GFP immunofluorescence and brightfield images of RPE
GFP immunofluorescence and brightfield images of RPE
SAEC Model
SAEC Model
Testing the effect of novel therapeutic on retinal organoids
Testing the effect of novel therapeutic on retinal organoids
CBF
CBF

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