Latest Publication: Read our teams’ latest paper in Antibiotics, showing reduced nephrotoxicity of a novel formulation of polymyxin B compared to the clinical formulation using a validated primary human proximal tubule cell model.
Keith Pye, Elena Tasinato, Siannah Shuttleworth, Claire Devlin and Colin Brown
Find out moreSumathy Mathialagan, Git Chung, Keith Pye, A. David Rodrigues, Manthena V. S. Varma and Colin Brown
Find out moreAlex Gledhill, Rachael Bowen, Michael Bartels, Andrew Bond, Git Chung, Colin D. A. Brown, Keith Pye & Tarang Vora
Find out moreThe aProximateTM model for renal drug safety/efficacy and transporter studies
Developing predictive in vitro Glomerulus , Proximal Tubule and Loop of Henle renal cell model platforms to investigate the renal uptake and nephrotoxic liability of large molecules
An in vitro model that predicts Antibiotic Renal Toxicity
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