Announcement:

New scientific publication in collaboration with the University of Newcastle on modelling Stargardt disease (STGD1) in vitro with retinal organoids (RO) to unravel genotype-phenotype correlations

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Resources

Scientific Publications

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Posters

Utilization of high – content imaging for the study of lung fibrosis

High content imaging (HCI) assays enable the study of the fibrotic processes: fibroblast – to – myofibroblast transition (FMT) and epithelial – to – mesenchymal transition (EMT)

Modelling Epithelial Barrier Function and Mucociliary Clearance Using Small Airway Epithelium Cells

Fact Sheets

Ciliary beat frequency analysis assay for lung small airway epithelium cells (SAEC)

Small airway epithelial cell (SAEC) model

High throughput, high sensitivity (HTHS) lung fibroblast-to-myofibroblasts transition (FMT) assay for anti-fibrotic drug screening

Press releases

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Scientific eBooks and Protocols

Lung models eBook

Q&A with our scientists

Dr Fiona Leslie

Meet the scientists: Dr Fiona Leslie, the scientist behind the development of the advanced FMT assay

Meet the scientists: Anusha Gupta, the scientist behind the development of the CBF assay

Dr Megan Webster

The inside story of lung in vitro models with Dr Megan Webster

Videos and Webinars

Dr Mike Nicholds – How Newcells works with Clients

Dr Mike Nicholds – Newcells Offerings

Creating a Powerful NAM respiratory Toxicology Strategy for Clinical Predictivity and IND success

Case Studies

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Quantitative Fibroblast-to-Myofibroblast Transition (FMT) studies

Quantitative FMT assay with high content imaging

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Human Lung Fibroblasts stimulated with TGF-β for 72 hours and immunostained to detect α-SMA, as a measure of extracellular matrix production and deposition.

In vitro evaluation of ocular toxicity and phenotypic rescue

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Newcells Biotech to develop 3D retinal organoids using hiPSC derived skin cells

In vitro selection of the most relevant species to predict human renal toxicity

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Evaluation of glomerular ADC toxicity in podocytes

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Isolated primary podocytes immunostained for cilia

Gene therapy viral vector assessment on retinal organoids

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Gene therapy viral vector assessment on RPE cells

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RPE

Predicting human renal injury from antisense oligonucleotide (ASO)

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