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Announcement:

Now launched! Ciliary beat frequency analysis assay for small airway epithelium cells - rapid compound analysis with enhanced sensitivity

State-of-the-Art Imaging Suite

Advantages of our comprehensive imaging suite

1.

High-throughput screening and multiplexing

2.

High-sensitivity for robust data

3.

More data for confident decision making

High-content imaging (HCI)

Enhanced sensitivity for high quality images to obtain accurate quantitative analyses. The suite offers integrated solutions for target localisation, phenotypic analyses, safety and efficacy studies. The high-content image analysis improves data accuracy and robustness for confident advancement of lead compounds.

Retinal organoids at D180 of differentiation stained with Hoechst and Rhodopsin analysed with Axio Observer with Apotome 3 system (Zeiss) .

Automated high-throughput analysis (HTS)

Rapid laser-based imaging enables high throughput capacity up to 1536-well plate. This is further enhanced with increased imaging speed and reduced analysis time to accelerate screening of large number of compounds and concentrations. The automated analysis provides more accurate and standardised results.

Fibroblast-to-myofibroblast (FMT) assay analysed with ImageXpress® Confocal HT.ai High-Content Imaging System (Molecular Devices) showing extracellular collagen deposition (pink), alpha smooth muscle actin (green) and cell nuclei (blue)

Imaging Capabilities

  • Axio Observer with Apotome 3 system (Zeiss) recommended for high resolution imaging with optical sectioning in fluorescence-based imaging to analyse complex cell models and tissues
  • ImageXpress® Pico Automated Cell Imaging system (Molecular Devices) ideal for high-throughput imaging. The automated analysis allows for even faster drug screening.
  • ImageXpress® Confocal HT.ai High-Content Imaging system (Molecular Devices) combines high-throughput, high-content and high-sensitivity imaging. The automated image analysis enables the capture of phenotypic details for more accurate data outputs and more confident decision making without bias. The higher sensitivity ensures identification of all active target compounds.

Newcells Biotech Imaging Capabilities

See our state-of-the-art imaging suite

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