In vitro tissue models that mimic in vivo human physiology to improve drug discovery
Our latest paper in collaboration with Pfizer on the role of OCT2/MATE in creatinine clearance is accepted in JPET.
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Michelle E. McClements, Hannah Steward, William Atkin, Emily Archer Goode, Carolina Gándara, Valeria Chichagova, and Robert E. MacLaren
Retinal Organoids eBook
Quantitative Fibroblast-to-Myofibroblast Transition (FMT) studies
Quantitative FMT assay with high content imaging
In vitro evaluation of ocular toxicity and phenotypic rescue
In vitro selection of the most relevant species to predict human renal toxicity
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