Announcement:

Our latest paper in collaboration with Pfizer on the role of OCT2/MATE in creatinine clearance is accepted in JPET.

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Resources

Articles and Posters

Tropism of AAV Vectors in Photoreceptor-Like Cells of Human iPSC-Derived Retinal Organoids

Tropism of AAV Vectors in Photoreceptor-Like Cells of Human iPSC-Derived Retinal Organoids

Michelle E. McClements, Hannah Steward, William Atkin, Emily Archer Goode, Carolina Gándara, Valeria Chichagova, and Robert E. MacLaren

Scientific eBooks and Protocols

The front cover of the retinal organoid ebook

Retinal Organoids eBook

Q&A with our scientists

Q&A with Dr Carolina Gandara, Head of retina assay development

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Latest trends in Retinal Organoids: Scientific chat with Dr Valeria Chichagova

Videos and Webinars

Newcells Biotech

Retinal Model Capabilities

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Meet Dr Valeria Chichagova – Our Associate Director of iPSC technology and Head of Retina

Newcells Biotech

Retinal organoids as a tool for in vitro pre-clinical testing

Case Studies

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Quantitative Fibroblast-to-Myofibroblast Transition (FMT) studies

Quantitative FMT assay with high content imaging

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Human Lung Fibroblasts stimulated with TGF-β for 72 hours and immunostained to detect α-SMA, as a measure of extracellular matrix production and deposition.

In vitro evaluation of ocular toxicity and phenotypic rescue

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Newcells Biotech to develop 3D retinal organoids using hiPSC derived skin cells

In vitro selection of the most relevant species to predict human renal toxicity

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A microscope image of a nephron model