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Latest Publication: Read our teams’ latest paper in Antibiotics, showing reduced nephrotoxicity of a novel formulation of polymyxin B compared to the clinical formulation using a validated primary human proximal tubule cell model.
Modeling Fibroblast-to-Myofibroblast Transition (FMT)
TGF-β1 mediated activation of fibroblasts, their transition to α-SMA expressing myofibroblasts, and associated increase in the expression and deposition of extracellular matrix proteins represents one of the underlying pathologic mechanisms of fibrosis.
7th December, 2023
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