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Home › Resources › Posters › The aProximate™ in vitro renal proximal tubule cell model as a platform to investigate the renal uptake and nephrotoxic liability of Antisense Oligonucleotide drug molecules

The aProximate™ in vitro renal proximal tubule cell model as a platform to investigate the renal uptake and nephrotoxic liability of Antisense Oligonucleotide drug molecules

Many biologics accumulate in the kidney and may cause unforeseen kidney injury.

Currently there is no in vitro platform that enables cross-species comparisons of drug transport or nephrotoxicity

Published

16th June, 2023

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