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A storyboard of renal transport

In vitro models for accurate prediction of renal tubular xenobiotic transport in vivo

Jelle Vriend, Keith R. Pye, Colin Brown. Current Opinion in Toxicology. 2021; 25: 15-22

A microscope image of a proximal tubule

Development of a novel predictive in vitro non human primate proximal tubule model for drug transporter & nephrotoxicity studies

Colin Brown Drug Metabolism and Pharmacokinetics. 2019; 34(1):S53

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Characterisation of human tubular cell monolayers as a model of proximal tubular xenobiotic handling

Colin D. A. Brown, Rachel Sayer, Amy S Windass, Iain S Haslam, Marc E De Broe, Patrick C D’Haese, Anja Verhulst Toxicology and Applied Pharmacology. 2008; 233(3): 428-438

Newcells Biotech

Primary human proximal tubule cell monolayers as a predictive model of renal phosphate homeostasis in heath & disease

Colin D. A. Brown. Drug Metabolism and Pharmacokinetics. 2017; 32(1): S14-S15

Newcells Biotech

P52 – Determination of aminoglycoside toxicity in human renal proximal tubule monolayers using clinical relevant biomarkers of nephrotoxicity

Colin Brown, Lyle Armstrong, Mike Nicholds, Git Nicholds Drug Metabolism and Pharmacokinetics. 2020; 35(1):S37

Newcells Biotech

Characterization of cisplatin toxicity in aProximate™ human proximal tubule cell monolayers

Colin Brown, Git Chung, Lyle Armstrong, Mike Nicholds Drug Metabolism and Pharmacokinetics. 2019; 34(1): S52-S53; SOT 2019 P105

Newcells Biotech

Human primary proximal tubule cell monolayers as a novel predictive model of nephrotoxicity

Git Chung, Sarah Billington, R. D. Wilde, Colin Brown Toxicology Letters. 2016;258:S139-S140

Application of organoid technology for retinal disease modelling and drug discovery

Application of organoid technology for retinal disease modelling & drug discovery

Valeria Chichagova. Drug Target Review. June 2020.

Newcells Biotech

c-Rel orchestrates energy-dependent epithelial & macrophage reprogramming in fibrosis

Nature Metabolism. 2020; 2:1350–1367