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Quantification analysis of immunopositive cells in control and RT organoids.

Room temperature shipment does not affect the biological activity of pluripotent stem cell derived retinal organoids

Maria Georgiou et al. PLoS ONE. 2020; 15(6), e0233860. 

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Human iPSC differentiation to retinal organoids.

Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line- & method-dependent

Valeria Chichagova, Gerrit Hilgen, Ali Ghareeb, Maria Georgiou, Madeleine Carter, Evelyne Sernagor, Majlinda Lako, Lyle Armstrong Stem Cells. 2020; 38(2):195-201

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Differentiation of retinal organoids from human pluripotent stem cells

Valeria Chichagova, Birthe Dorgau, Majed Felemban, Maria Georgiou, Lyle Armstrong, Majlinda Lako Current Protocols in Stem Cell Biology. 2019; 50(1):e95

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The importance of incorporating OCT2 plasma membrane expression and membrane potential in IVIVE of metformin renal secretory clearance

Vineet Kumar, Jia Yin, Sarah Billington, Bhagwat Prasad, Colin D A Brown, Joanne Wang, Jashvant D Unadkat Drug Metabolism and Disposition. 2018; 46(10):1441-1445

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Diagrammatic representation of the culture formats for both single and pooled retinal organoids

Human-induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient-dependent efficiency

Stem Cells. 2018; 36(10):1535-1551

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Newcells Biotech

Using statistical models to identify key variables critical for generation of retinal organoids from iPSC

Valeria Chichagova, Dean Hallam, Mike Nicholds, Robert Thomas, Majlinda Lako, Lyle Armstrong Investigative Ophthalmology & Visual Science. 2018; 59(9): 565

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Derivation of a system-independent Ki for p-glycoprotein mediated digoxin transport from system-dependent IC50 data

Derivation of a system-independent Ki for p-glycoprotein mediated digoxin transport from system-dependent IC50 data

Aqsaa Chaudhry, Git Chung, Adam Lynn, Akshata Yalvigi, Colin Brown, Harma Ellens, Michael O’Connor, Caroline Lee, Joe Bentz Drug Metabolism and Disposition. 2018; 46(3): 279-290

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Abundance of drug transporters in the human kidney cortex as quantified by quantitative targeted proteomics

Bhagwat Prasad, Katherine Johnson, Sarah Billington, Caroline Lee, Git W Chung, Colin D A Brown, Edward J Kelly, Jonathan Himmelfarb, Jashvant D Unadkat Drug Metabolism and Disposition. 2018; 46(3): 279-290

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Newcells Biotech

The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression & function in the proximal tubule

Sarah E. Jenkinson, Git W Chung, Ellen van Loon, Nur S Bakar, Abigail M Dalzell, Colin D A Brown Pflügers Archiv European Journal of Physiology. 2012; 464(6): 601-11

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