Announcement:

The results of a recent collaboration between Sanofi, GSK, Lilly, Vesalius Therapeutics, Leiden University, Heidelberg University, ElmorePathology and Newcells aimed at enhancing safety assessments has just been published. Find out how rat kidney gene co-expression networks has enabled biomarker identification and human translation for renal safety assessments.

Find out more

A man writing something in a notebook

Home › Resources › Scientific publications › Page 3

Resources: Scientific publications - Page 3

Newcells Biotech

Human primary proximal tubule cell monolayers as a novel predictive model of nephrotoxicity

Git Chung, Sarah Billington, R. D. Wilde, Colin Brown Toxicology Letters. 2016;258:S139-S140

Application of organoid technology for retinal disease modelling and drug discovery

Application of organoid technology for retinal disease modelling & drug discovery

Valeria Chichagova. Drug Target Review. June 2020.

Newcells Biotech

c-Rel orchestrates energy-dependent epithelial & macrophage reprogramming in fibrosis

Nature Metabolism. 2020; 2:1350–1367

Enhancing the immune function of hiPSC-derived retinal organoids.

Enhancing immune function of hiPSC-derived retinal organoids by incorporating microglial cells

Valeria Chichagova, Maria Georgiou, Birthe Dorgau, Madeleine Carter, Git Chung, Evelyne Sernagor, Lyle Armstrong, Majlinda Lako Investigative Ophthalmology & Visual Science. 2020; 61(7)

Quantification analysis of immunopositive cells in control and RT organoids.

Room temperature shipment does not affect the biological activity of pluripotent stem cell derived retinal organoids

Maria Georgiou et al. PLoS ONE. 2020; 15(6), e0233860.

In vitro platforms for de-risking nephrotoxicity during drug development

Dr Sandy Primrose & Dr Colin Brown Drug Target Review. March 2020

Human iPSC differentiation to retinal organoids.

Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line- & method-dependent

Valeria Chichagova, Gerrit Hilgen, Ali Ghareeb, Maria Georgiou, Madeleine Carter, Evelyne Sernagor, Majlinda Lako, Lyle Armstrong Stem Cells. 2020; 38(2):195-201

Newcells Biotech

Differentiation of retinal organoids from human pluripotent stem cells

Valeria Chichagova, Birthe Dorgau, Majed Felemban, Maria Georgiou, Lyle Armstrong, Majlinda Lako Current Protocols in Stem Cell Biology. 2019; 50(1):e95

Newcells Biotech

The importance of incorporating OCT2 plasma membrane expression and membrane potential in IVIVE of metformin renal secretory clearance

Vineet Kumar, Jia Yin, Sarah Billington, Bhagwat Prasad, Colin D A Brown, Joanne Wang, Jashvant D Unadkat Drug Metabolism and Disposition. 2018; 46(10):1441-1445

Book a Call