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Analysis of the effect of a compound on retinal microtissue composition

Development of a human in vitro model for retinitis pigmentosa

Assessing the validity of a nephron model for a metabolic disease study

Predicting renal retention of radioconjugates in a human relevant in vitro model

Safety and efficacy evaluation of a novel therapeutic AAV vectors using a human retinal organoid model

GFP immunofluorescence and brightfield images of RPE

Comparing the transduction efficiency of two AAV vectors in RPE and Retinal Organoid models derived from iPSCs lines

Comprehensive toxicity study on retinal ganglion cells in early-stage human retinal organoids

Development and characterisation of an early-stage retinal organoid disease model (for non-ocular disease)

Human Lung Fibroblasts stimulated with TGF-β for 72 hours and immunostained to detect α-SMA, as a measure of extracellular matrix production and deposition.

Quantitative Fibroblast-to-Myofibroblast Transition (FMT) studies

Quantitative FMT assay with high content imaging

Newcells Biotech to develop 3D retinal organoids using hiPSC derived skin cells

Comprehensive in vitro evaluation of ocular toxicity and phenotypic rescue

In vitro selection of the most relevant species to predict human renal toxicity

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Isolated primary podocytes immunostained for cilia

Evaluation of glomerular ADC toxicity in podocytes

Gene therapy viral vector assessment on retinal organoids

RPE

Gene therapy viral vector assessment on RPE cells

Predicting human renal injury from antisense oligonucleotide (ASO)

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