Resources
Scientific Publications
View all
Derivation of a system-independent Ki for p-glycoprotein mediated digoxin transport from system-dependent IC50 data
Aqsaa Chaudhry, Git Chung, Adam Lynn, Akshata Yalvigi, Colin Brown, Harma Ellens, Michael O’Connor, Caroline Lee, Joe Bentz Drug Metabolism and Disposition. 2018; 46(3): 279-290
Find out more
Abundance of drug transporters in the human kidney cortex as quantified by quantitative targeted proteomics
Bhagwat Prasad, Katherine Johnson, Sarah Billington, Caroline Lee, Git W Chung, Colin D A Brown, Edward J Kelly, Jonathan Himmelfarb, Jashvant D Unadkat Drug Metabolism and Disposition. 2018; 46(3): 279-290
Find out more
The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression & function in the proximal tubule
Sarah E. Jenkinson, Git W Chung, Ellen van Loon, Nur S Bakar, Abigail M Dalzell, Colin D A Brown Pflügers Archiv European Journal of Physiology. 2012; 464(6): 601-11
Find out morePosters
View all
An inter-species comparison of the triclopyr in vitro and in vivo toxicokinetic properties, for risk assessment purpose
The aProximate™ in vitro renal proximal tubule cell model as a platform to investigate the renal uptake and nephrotoxic liability of biologics
Improved in vitro renal tubular drug transport modelling to meet challenges
Fact Sheets
View allSorry, there are currently no posts here. Please check back later.
Press releases
View allSorry, there are currently no posts here. Please check back later.
Scientific eBooks and Protocols
View allThere are currently no posts here. Please check back later.
Q&A with our scientists
View allSorry, there are currently no posts here. Please check back later.
Videos and Webinars
View allSorry, there are currently no posts here. Please check back later.
Case Studies
View allQuantitative Fibroblast-to-Myofibroblast Transition (FMT) studies
Quantitative FMT assay with high content imaging
Find out more
In vitro evaluation of ocular toxicity and phenotypic rescue
Find out more
In vitro selection of the most relevant species to predict human
Evaluation of glomerular ADC toxicity in podocytes
Find out more
Gene therapy viral vector assessment on retinal organoids
Find out more
Gene therapy viral vector assessment on RPE cells
Find out more
Predicting human renal injury from antisense oligonucleotide (ASO)
Find out more
