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Scientific Publications
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Tropism of AAV Vectors in Photoreceptor-Like Cells of Human iPSC-Derived Retinal Organoids
Michelle E. McClements, Hannah Steward, William Atkin, Emily Archer Goode, Carolina Gándara, Valeria Chichagova, and Robert E. MacLaren
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Review of pharmacokinetics & metabolism of triclopyr herbicide in mammals: Impact on safety assessments
Michael Bartels, Colin Brown, Git Chung, Melissa Chan, Claire Terry, Sean Gehen, Marco Corvaro Regulatory toxicology and pharmacology. 2020; 116:104714
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Development of a novel predictive in vitro non human primate proximal tubule model for drug transporter & nephrotoxicity studies
Colin Brown Drug Metabolism and Pharmacokinetics. 2019; 34(1):S53
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Modelling Epithelial Barrier Function and Mucociliary Clearance Using Small Airway Epithelium Cells
A high-throughput, in vitro assessment of antibiotic induced podocyte injury
A Primary Human in vitro Focal Segmental Glomerulosclerosis (FSGS) model for drug development applications
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Case Studies
View allQuantitative Fibroblast-to-Myofibroblast Transition (FMT) studies
Quantitative FMT assay with high content imaging
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In vitro evaluation of ocular toxicity and phenotypic rescue
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In vitro selection of the most relevant species to predict human
Evaluation of glomerular ADC toxicity in podocytes
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Gene therapy viral vector assessment on retinal organoids
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Gene therapy viral vector assessment on RPE cells
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Predicting human renal injury from antisense oligonucleotide (ASO)
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