Announcement:

Latest Publication: Read our teams’ latest paper in Antibiotics, showing reduced nephrotoxicity of a novel formulation of polymyxin B compared to the clinical formulation using a validated primary human proximal tubule cell model.

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Resources

Scientific Publications

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Posters

An in-vitro high-content imaging assay for the study of fibroblast activation and matrix deposition

the glomerulus

Developing a Comprehensive Biomarker Package for Detecting Drug-Induced Injury in Podocytes

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Lung Model Aids SARS-CoV-2 Research

Fact Sheets

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Press releases

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Scientific eBooks and Protocols

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Q&A with our scientists

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Videos and Webinars

Newcells Biotech

Retinal organoids as a tool for in vitro pre-clinical testing

Newcells Biotech

Primary Kidney Cells for Modelling Chronic Kidney Disease in vitro

Dr Kathryn Garner, PhD

Developing High Content Imaging Assays for Chronic Kidney Disease

Case Studies

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Quantitative Fibroblast-to-Myofibroblast Transition (FMT) studies

Quantitative FMT assay with high content imaging

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Human Lung Fibroblasts stimulated with TGF-β for 72 hours and immunostained to detect α-SMA, as a measure of extracellular matrix production and deposition.

In vitro evaluation of ocular toxicity and phenotypic rescue

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Newcells Biotech to develop 3D retinal organoids using hiPSC derived skin cells

In vitro selection of the most relevant species to predict human renal toxicity

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A microscope image of a nephron model

Evaluation of glomerular ADC toxicity in podocytes

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