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High content imaging (HCI) assays enable the study of the fibrotic processes: fibroblast – to – myofibroblast transition (FMT) and epithelial – to – mesenchymal transition (EMT)

  • Discover about how excessive and abnormal deposition of extracellular matrix (ECM) is a characteristic feature of fibrotic lung disease, such as idiopathic pulmonary fibrosis (IPF).
  • Learn about how repetitive injury to lower airway epithelial cells drives epithelial-to-mesenchymal transition (EMT).
  • In this study, we model FMT and EMT process in-vitro using high content imaging (HCI) enables compound screening to assist anti-fibrotic drug discovery. 
Published

17th June, 2024

Published by

Fiona Leslie, Oliver Birch, Chloe Whiting, Megan Webster

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