In vitro tissue models that mimic in vivo human physiology to improve drug discovery
In vitro tissue models that mimic in vivo human physiology to improve drug discovery
In vitro tissue models that mimic in vivo human physiology to improve drug discovery
Latest Publication: Read our teams’ latest paper in Antibiotics, showing reduced nephrotoxicity of a novel formulation of polymyxin B compared to the clinical formulation using a validated primary human proximal tubule cell model.
Home › Resources › Posters › The aProximate™ in vitro renal proximal tubule cell model as a platform to investigate the renal uptake and nephrotoxic liability of Antisense Oligonucleotide drug molecules
16th June, 2023
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Many biologics accumulate in the kidney and may cause unforeseen kidney injury.
Currently there is no in vitro platform that enables cross-species comparisons of drug transport or nephrotoxicity
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