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Derivation of a system-independent Ki for p-glycoprotein mediated digoxin transport from system-dependent IC50 data

Derivation of a system-independent Ki for p-glycoprotein mediated digoxin transport from system-dependent IC50 data

Aqsaa Chaudhry, Git Chung, Adam Lynn, Akshata Yalvigi, Colin Brown, Harma Ellens, Michael O’Connor, Caroline Lee, Joe Bentz Drug Metabolism and Disposition. 2018; 46(3): 279-290

Abundance of drug transporters in the human kidney cortex as quantified by quantitative targeted proteomics

Bhagwat Prasad, Katherine Johnson, Sarah Billington, Caroline Lee, Git W Chung, Colin D A Brown, Edward J Kelly, Jonathan Himmelfarb, Jashvant D Unadkat Drug Metabolism and Disposition. 2018; 46(3): 279-290

Newcells Biotech

The limitations of renal epithelial cell line HK-2 as a model of drug transporter expression & function in the proximal tubule

Sarah E. Jenkinson, Git W Chung, Ellen van Loon, Nur S Bakar, Abigail M Dalzell, Colin D A Brown Pflügers Archiv European Journal of Physiology. 2012; 464(6): 601-11

Newcells Biotech

The breast cancer resistance protein transporter ABCG2 is expressed in the human kidney proximal tubule apical membrane

M. Huls, C D A Brown, A S Windass, R Sayer, J J M W van den Heuvel, S Heemskerk, F G M Russel, R Masereeuw Kindey International. 2008; 73(2): 220-5