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New scientific publication in collaboration with the University of Newcastle on modelling Stargardt disease (STGD1) in vitro with retinal organoids (RO) to unravel genotype-phenotype correlations

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Scientific Publications

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Tropism of AAV Vectors in Photoreceptor-Like Cells of Human iPSC-Derived Retinal Organoids

Tropism of AAV Vectors in Photoreceptor-Like Cells of Human iPSC-Derived Retinal Organoids

Michelle E. McClements, Hannah Steward, William Atkin, Emily Archer Goode, Carolina Gándara, Valeria Chichagova, and Robert E. MacLaren

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Posters

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Fact Sheets

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iPSC-derived Retinal Organoids (RO)

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Press releases

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Scientific eBooks and Protocols

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The front cover of the retinal organoid ebook

Retinal Organoids eBook

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Q&A with our scientists

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Q&A with Dr Carolina Gandara, Head of retina assay development

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Latest trends in Retinal Organoids: Scientific chat with Dr Valeria Chichagova

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Videos and Webinars

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Dr Mike Nicholds – How Newcells works with Clients

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Dr Mike Nicholds – Newcells Offerings

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Webinar

Moving compounds to IND using predictive retina models

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Case Studies

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Quantitative Fibroblast-to-Myofibroblast Transition (FMT) studies

Quantitative FMT assay with high content imaging

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Human Lung Fibroblasts stimulated with TGF-β for 72 hours and immunostained to detect α-SMA, as a measure of extracellular matrix production and deposition.

In vitro evaluation of ocular toxicity and phenotypic rescue

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Newcells Biotech to develop 3D retinal organoids using hiPSC derived skin cells

In vitro selection of the most relevant species to predict human renal toxicity

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Evaluation of glomerular ADC toxicity in podocytes

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Isolated primary podocytes immunostained for cilia

Gene therapy viral vector assessment on retinal organoids

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Gene therapy viral vector assessment on RPE cells

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RPE

Predicting human renal injury from antisense oligonucleotide (ASO)

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