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Home › Resources › Articles and posters › The aProximate™ in vitro renal proximal tubule cell model as a platform to investigate the renal uptake and nephrotoxic liability of Antisense Oligonucleotide drug molecules

The aProximate™ in vitro renal proximal tubule cell model as a platform to investigate the renal uptake and nephrotoxic liability of Antisense Oligonucleotide drug molecules

Published

16th June, 2023

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Many biologics accumulate in the kidney and may cause unforeseen kidney injury.

Currently there is no in vitro platform that enables cross-species comparisons of drug transport or nephrotoxicity

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