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Resources

Scientific Publications

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Enhancing the immune function of hiPSC-derived retinal organoids.

Enhancing immune function of hiPSC-derived retinal organoids by incorporating microglial cells

Valeria Chichagova, Maria Georgiou, Birthe Dorgau, Madeleine Carter, Git Chung, Evelyne Sernagor, Lyle Armstrong, Majlinda Lako Investigative Ophthalmology & Visual Science. 2020; 61(7)

Quantification analysis of immunopositive cells in control and RT organoids.

Room temperature shipment does not affect the biological activity of pluripotent stem cell derived retinal organoids

Maria Georgiou et al. PLoS ONE. 2020; 15(6), e0233860.

Human iPSC differentiation to retinal organoids.

Human iPSC differentiation to retinal organoids in response to IGF1 and BMP4 activation is line- & method-dependent

Valeria Chichagova, Gerrit Hilgen, Ali Ghareeb, Maria Georgiou, Madeleine Carter, Evelyne Sernagor, Majlinda Lako, Lyle Armstrong Stem Cells. 2020; 38(2):195-201

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Fact Sheets

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Press releases

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Scientific eBooks and Protocols

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Q&A with our scientists

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Videos and Webinars

Dr Mike Nicholds – About the company

Retinal Model Capabilities

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Meet Dr Valeria Chichagova – Our Associate Director of iPSC technology and Head of Retina

Case Studies

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Quantitative Fibroblast-to-Myofibroblast Transition (FMT) studies

Quantitative FMT assay with high content imaging

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Human Lung Fibroblasts stimulated with TGF-β for 72 hours and immunostained to detect α-SMA, as a measure of extracellular matrix production and deposition.

In vitro evaluation of ocular toxicity and phenotypic rescue

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Newcells Biotech to develop 3D retinal organoids using hiPSC derived skin cells

In vitro selection of the most relevant species to predict human renal toxicity

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A microscope image of a nephron model

Evaluation of glomerular ADC toxicity in podocytes

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Gene therapy viral vector assessment on retinal organoids

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Gene therapy viral vector assessment on RPE cells

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