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Scientific Publications

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Newcells Biotech

Differentiation of retinal organoids from human pluripotent stem cells

Valeria Chichagova, Birthe Dorgau, Majed Felemban, Maria Georgiou, Lyle Armstrong, Majlinda Lako Current Protocols in Stem Cell Biology. 2019; 50(1):e95

Diagrammatic representation of the culture formats for both single and pooled retinal organoids

Human-induced pluripotent stem cells generate light responsive retinal organoids with variable and nutrient-dependent efficiency

Stem Cells. 2018; 36(10):1535-1551

Newcells Biotech

Using statistical models to identify key variables critical for generation of retinal organoids from iPSC

Valeria Chichagova, Dean Hallam, Mike Nicholds, Robert Thomas, Majlinda Lako, Lyle Armstrong Investigative Ophthalmology & Visual Science. 2018; 59(9): 565

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Fact Sheets

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Press releases

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Scientific eBooks and Protocols

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Q&A with our scientists

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Videos and Webinars

Retinal organoids as a tool for in vitro pre-clinical testing

Retinal Organoids as an Emerging Tool for Drug Discovery

NIH/NEI 3D-ROC Sponsor Webinar

NIH/NEI 3D-ROC Sponsor Webinar

Case Studies

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Quantitative Fibroblast-to-Myofibroblast Transition (FMT) studies

Quantitative FMT assay with high content imaging

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Human Lung Fibroblasts stimulated with TGF-β for 72 hours and immunostained to detect α-SMA, as a measure of extracellular matrix production and deposition.

In vitro evaluation of ocular toxicity and phenotypic rescue

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Newcells Biotech to develop 3D retinal organoids using hiPSC derived skin cells

In vitro selection of the most relevant species to predict human renal toxicity

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A microscope image of a nephron model

Evaluation of glomerular ADC toxicity in podocytes

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Gene therapy viral vector assessment on retinal organoids

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Gene therapy viral vector assessment on RPE cells

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