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Scientific Publications
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Characterization of cisplatin toxicity in aProximate™ human proximal tubule cell monolayers
Colin Brown, Git Chung, Lyle Armstrong, Mike Nicholds Drug Metabolism and Pharmacokinetics. 2019; 34(1): S52-S53; SOT 2019 P105
Find out moreHuman primary proximal tubule cell monolayers as a novel predictive model of nephrotoxicity
Git Chung, Sarah Billington, R. D. Wilde, Colin Brown Toxicology Letters. 2016;258:S139-S140
Find out moreThe importance of incorporating OCT2 plasma membrane expression and membrane potential in IVIVE of metformin renal secretory clearance
Vineet Kumar, Jia Yin, Sarah Billington, Bhagwat Prasad, Colin D A Brown, Joanne Wang, Jashvant D Unadkat Drug Metabolism and Disposition. 2018; 46(10):1441-1445
Find out morePosters
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The aProximate™ in vitro renal proximal tubule cell model as a platform to investigate the renal uptake & nephrotoxic liability of Antisense Oligonucleotide drug molecules
A solution for shipping primary human proximal tubule cell monolayers between laboratories
Development of highly-differentiated human primary proximal tubule MPS model
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Case Studies
View allQuantitative Fibroblast-to-Myofibroblast Transition (FMT) studies
Quantitative FMT assay with high content imaging
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In vitro evaluation of ocular toxicity and phenotypic rescue
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In vitro selection of the most relevant species to predict human
Evaluation of glomerular ADC toxicity in podocytes
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Gene therapy viral vector assessment on retinal organoids
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Gene therapy viral vector assessment on RPE cells
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