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Primary Kidney Cells for Modelling Chronic Kidney Disease in vitro

https://www.youtube.com/watch?v=1lXoNeQsCfY

Date

March 28, 2023

Presented by

Dr Kathryn Garner, PhD

Human podocytes maintain high levels of key podocyte markers, including nephrin, podocin, WT1, CD2AP.
Well-validated Podocyte Toxicity Assay senses injury through barrier integrity (TEER) measures and passage of fluorescently-labelled dextran molecules.
Disease modelling in podocytes, proximal tubule cells and renal fibroblasts with monitoring of fibrosis readouts – matrix deposition – using high content imaging.

Find out more about our glomerulus model and kidney toxicity assays

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