A recent study by a team at Unilever has demonstrated the predictive power of NAM approaches for the comprehensive safety assessment of compounds by combining in vitro models with advanced computational techniques. They used the aProximate™ proximal tubule cell model to assess potential nephrotoxicity and renal transport kinetics.
Keith Pye, Elena Tasinato, Siannah Shuttleworth, Claire Devlin and Colin Brown
Find out moreGeneration of a physiologically relevant in vitro model of autosomal dominant Retinitis Pigmentosa caused by RHO-P23H mutation using 3D retinal organoids
Utilization of high – content imaging for the study of lung fibrosis
High content imaging (HCI) assays enable the study of the fibrotic processes: fibroblast – to – myofibroblast transition (FMT) and epithelial – to – mesenchymal transition (EMT)