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Scientific Publications

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Newcells Biotech

Characterization of cisplatin toxicity in aProximate™ human proximal tubule cell monolayers

Colin Brown, Git Chung, Lyle Armstrong, Mike Nicholds Drug Metabolism and Pharmacokinetics. 2019; 34(1): S52-S53; SOT 2019 P105

Newcells Biotech

P52 – Determination of aminoglycoside toxicity in human renal proximal tubule monolayers using clinical relevant biomarkers of nephrotoxicity

Colin Brown, Lyle Armstrong, Mike Nicholds, Git Nicholds Drug Metabolism and Pharmacokinetics. 2020; 35(1):S37

Freshly isolated primary human proximal tubule cells as an in vitro model for the detection of renal tubular toxicity

Freshly isolated primary human proximal tubule cells as an in vitro model for the detection of renal tubular toxicity

Piyush Bajaj, Git Chung, Keith Pye, Tomoya Yukawa, Akio Imanishi, Yuichi Takai, Colin Brown, Matthew P.Wagoner
Toxicology. 2020; 442:152535

Posters

A high-throughput, in vitro assessment of antibiotic induced podocyte injury

A Primary Human in vitro Focal Segmental Glomerulosclerosis (FSGS) model for drug development applications

An in vitro Human Primary Thick Ascending Limb Model For The Assessment of Compound Nephrotoxicity

Fact Sheets

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Press releases

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Scientific eBooks and Protocols

The front cover of the aProximate ebook

Renal Proximal Tubule Cells Model eBook

Q&A with our scientists

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Q&A with Dr Carolina Gandara, Head of retina assay development

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Latest trends in Retinal Organoids: Scientific chat with Dr Valeria Chichagova

Videos and Webinars

Dr Mike Nicholds – Newcells Offerings

Dr Mike Nicholds – How Newcells works with Clients

Creating a Powerful NAM respiratory Toxicology Strategy for Clinical Predictivity and IND success

Case Studies

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Quantitative Fibroblast-to-Myofibroblast Transition (FMT) studies

Quantitative FMT assay with high content imaging

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Human Lung Fibroblasts stimulated with TGF-β for 72 hours and immunostained to detect α-SMA, as a measure of extracellular matrix production and deposition.

In vitro evaluation of ocular toxicity and phenotypic rescue

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Newcells Biotech to develop 3D retinal organoids using hiPSC derived skin cells

In vitro selection of the most relevant species to predict human renal toxicity

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A microscope image of a nephron model

Evaluation of glomerular ADC toxicity in podocytes

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Gene therapy viral vector assessment on retinal organoids

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Gene therapy viral vector assessment on RPE cells

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RPE