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Resources

Scientific Publications

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Newcells Biotech

Review of pharmacokinetics & metabolism of triclopyr herbicide in mammals: Impact on safety assessments

Michael Bartels, Colin Brown, Git Chung, Melissa Chan, Claire Terry, Sean Gehen, Marco Corvaro Regulatory toxicology and pharmacology. 2020; 116:104714

Newcells Biotech

The importance of incorporating OCT2 plasma membrane expression and membrane potential in IVIVE of metformin renal secretory clearance

Vineet Kumar, Jia Yin, Sarah Billington, Bhagwat Prasad, Colin D A Brown, Joanne Wang, Jashvant D Unadkat Drug Metabolism and Disposition. 2018; 46(10):1441-1445

Derivation of a system-independent Ki for p-glycoprotein mediated digoxin transport from system-dependent IC50 data

Derivation of a system-independent Ki for p-glycoprotein mediated digoxin transport from system-dependent IC50 data

Aqsaa Chaudhry, Git Chung, Adam Lynn, Akshata Yalvigi, Colin Brown, Harma Ellens, Michael O’Connor, Caroline Lee, Joe Bentz Drug Metabolism and Disposition. 2018; 46(3): 279-290

Posters

A predictive in vitro primary proximal tubule platform for derisking of antibiotic-induced kidney injury

A Sensitive Nephrotoxicity Assay of in vitro Podocyte Effacement

A Live Cell High Content Imaging Assay for Monitoring Large Molecules Uptake into aProximateTM Proximal Tubule Epithelial Cells via Megalin and Cubulin

Fact Sheets

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Press releases

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Scientific eBooks and Protocols

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Q&A with our scientists

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Videos and Webinars

Lung Model Capabilities

Retinal Model Capabilities

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Meet Dr Valeria Chichagova – Our Associate Director of iPSC technology and Head of Retina

Case Studies

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Quantitative Fibroblast-to-Myofibroblast Transition (FMT) studies

Quantitative FMT assay with high content imaging

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Human Lung Fibroblasts stimulated with TGF-β for 72 hours and immunostained to detect α-SMA, as a measure of extracellular matrix production and deposition.

In vitro evaluation of ocular toxicity and phenotypic rescue

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Newcells Biotech to develop 3D retinal organoids using hiPSC derived skin cells

In vitro selection of the most relevant species to predict human renal toxicity

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A microscope image of a nephron model

Evaluation of glomerular ADC toxicity in podocytes

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Gene therapy viral vector assessment on retinal organoids

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Gene therapy viral vector assessment on RPE cells

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