A man writing something in a notebook

Home › Resources › Page 4

Resources

Scientific Publications

View all

Cross species comparisons

aProximate™ as a novel, predictive model of aminoglycoside-induced nephrotoxicity

Keith Pye, Git Chung, Lyle Armstrong, Mike Nicholds, Colin Brown Abstracts of the 55th Congress of the European Societies of Toxicology (EUROTOX 2019) TOXICOLOGY SCIENCE PROVIDING SOLUTIONS. Toxicol Lett. 2019;314:S167–8.

A storyboard of renal transport

In vitro models for accurate prediction of renal tubular xenobiotic transport in vivo

Jelle Vriend, Keith R. Pye, Colin Brown. Current Opinion in Toxicology. 2021; 25: 15-22

Freshly isolated primary human proximal tubule cells as an in vitro model for the detection of renal tubular toxicity

Freshly isolated primary human proximal tubule cells as an in vitro model for the detection of renal tubular toxicity

Piyush Bajaj, Git Chung, Keith Pye, Tomoya Yukawa, Akio Imanishi, Yuichi Takai, Colin Brown, Matthew P.Wagoner
Toxicology. 2020; 442:152535

Posters

An in vitro Human Primary Thick Ascending Limb Model For The Assessment of Compound Nephrotoxicity

A predictive in vitro primary proximal tubule platform for derisking of antibiotic-induced kidney injury

Overcoming technical difficulties of in vitro assay – development

Fact Sheets

Sorry, there are currently no posts here. Please check back later.

Press releases

View all

Sorry, there are currently no posts here. Please check back later.

Scientific eBooks and Protocols

There are currently no posts here. Please check back later.

Q&A with our scientists

Sorry, there are currently no posts here. Please check back later.

Videos and Webinars

Retinal Model Capabilities

Image of a women

Meet Dr Valeria Chichagova – Our Associate Director of iPSC technology and Head of Retina

Retinal organoids as a tool for in vitro pre-clinical testing

Case Studies

View all

Quantitative Fibroblast-to-Myofibroblast Transition (FMT) studies

Quantitative FMT assay with high content imaging

Find out more

Human Lung Fibroblasts stimulated with TGF-β for 72 hours and immunostained to detect α-SMA, as a measure of extracellular matrix production and deposition.

In vitro evaluation of ocular toxicity and phenotypic rescue

Find out more

Newcells Biotech to develop 3D retinal organoids using hiPSC derived skin cells

In vitro selection of the most relevant species to predict human renal toxicity

Find out more

A microscope image of a nephron model

Evaluation of glomerular ADC toxicity in podocytes

Find out more

Gene therapy viral vector assessment on retinal organoids

Find out more

Gene therapy viral vector assessment on RPE cells

Find out more

RPE

Predicting human renal injury from antisense oligonucleotide (ASO)

Find out more