Announcement:

New scientific publication in collaboration with the University of Newcastle on modelling Stargardt disease (STGD1) in vitro with retinal organoids (RO) to unravel genotype-phenotype correlations

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Scientific Publications

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Posters

A Live Cell High Content Imaging Assay for Monitoring Large Molecules Uptake into aProximateTM Proximal Tubule Epithelial Cells via Megalin and Cubulin

Development of highly-differentiated human primary proximal tubule MPS model (aProximate MPS™ Flow)

The aProximate™ in vitro renal proximal tubule cell model as a platform to investigate the renal uptake and nephrotoxic liability of Antisense Oligonucleotide drug molecules

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Press releases

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Scientific eBooks and Protocols

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Q&A with our scientists

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Videos and Webinars

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Meet Dr Valeria Chichagova – Our Associate Director of iPSC technology and Head of Retina

Retinal organoids as a tool for in vitro pre-clinical testing

Retinal Organoids as an Emerging Tool for Drug Discovery

Case Studies

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Quantitative Fibroblast-to-Myofibroblast Transition (FMT) studies

Quantitative FMT assay with high content imaging

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Human Lung Fibroblasts stimulated with TGF-β for 72 hours and immunostained to detect α-SMA, as a measure of extracellular matrix production and deposition.

In vitro evaluation of ocular toxicity and phenotypic rescue

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Newcells Biotech to develop 3D retinal organoids using hiPSC derived skin cells

In vitro selection of the most relevant species to predict human renal toxicity

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Evaluation of glomerular ADC toxicity in podocytes

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Isolated primary podocytes immunostained for cilia

Gene therapy viral vector assessment on retinal organoids

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Gene therapy viral vector assessment on RPE cells

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RPE

Predicting human renal injury from antisense oligonucleotide (ASO)

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