Announcement:

Latest Publication: Read our teams’ latest paper in Antibiotics, showing reduced nephrotoxicity of a novel formulation of polymyxin B compared to the clinical formulation using a validated primary human proximal tubule cell model.

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Resources: Posters - Page 3

Comparison of multiple batches of human iPSC-derived retinal organoids produced at large scale

the glomerulus

Developing a Comprehensive Biomarker Package for Detecting Drug-Induced Injury in Podocytes

Albumin and siRNA Uptake by Megalin Cubulin.

The aProximate™ in vitro renal proximal tubule cell model as a platform to investigate the renal uptake & nephrotoxic liability of Antisense Oligonucleotide drug molecules

A microscope image of a nephron model

A solution for shipping primary human proximal tubule cell monolayers between laboratories

Kidney proximal tubule cells immunostained with ZO-1 following exposure to MPS flow

Development of highly-differentiated human primary proximal tubule MPS model

Isolated primary podocytes immunostained for cilia

MPS World Summit 2022: in vitro model of podocyte damage

Isolated primary podocytes immunostained for cilia

JSAAE Poster Presentation

Isolated primary podocytes immunostained for cilia

Complementary in vitro tools to investigate renal drug transport

Isolated primary podocytes immunostained for cilia

Development of a predictive in vitro human proximal tubule platform for de-risking nephrotoxicity