News - Page 5
Our commitment to the 3Rs
There are few topics more controversial than the use of animals in science, despite the enormous contribution animal experimentation continues to make to the development of new medicines and…
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Newcells Biotech secures over £5m for 3D tissue models
Newcastle-based human stem cell model specialists, Newcells Biotech, have secured a total of £5.25m worth of funding to accelerate their growth plans in the international life sciences market.The funding…
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Developing a 3D in vitro proximal tubule model for chronic toxicity studies
The kidney proximal tubule is of key interest in drug discovery. This is due to its primary role in the excretion and reabsorption of xenobiotics, such as drugs and…
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Covid-19 action plan – 2021 update
In line with our previous Covid-19 Action Plan, Newcells Biotech has continued to review and invest in measures to reduce the risk to its staff and…
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Improved in vitro renal tubular drug transport modelling to meet regulatory & development cost challenges
The proximal tubule is key due to its role in the excretion and reabsorption of many xenobiotic compounds. Due to the high costs associated with drug discovery and the…
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Development of a physiologically relevant lung model for understanding SARS-CoV-2 infection
Covid-19 is known to infect the lungs. However, the dynamics of viral infection and replication are poorly understood. Alongside the Liverpool School of Tropical Medicine, we…
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Diagnosing unresolved Stargardt disease using retina-specific splicing isoforms obtained from retinal organoids
At Newcells Biotech, we specialise in the large-scale production of retinal organoids for the purpose of in vitro toxicology efficacy studies and disease modelling. Our differentiation protocols generate organoids which…
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Development of functioning in vitro lung assay for modelling Covid-19 infection
Newcells Biotech, experts in induced pluripotent stem cell (iPSC) differentiation and assay construction, have confirmed their human lung epithelium model as an effective platform…
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Newcells scales up its operations in The Biosphere
Newcells Biotech, a pioneering life-sciences spin-out that applies Human induced Pluripotent Stem Cells (hiPSCs) to develop assays for drug development, have consolidated their two laboratory
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An overview of vaccine development & sub-types
Vaccination can be regarded as one of biomedicines biggest triumphs. Since Edward Jenner pioneered the smallpox vaccine in 1798, subsequent morbidity and mortality rates have
Read updateBiologics & the kidney – importance of transport & safety assessment
Biologics represent a new modality of drug molecules which is rapidly expanding in market share and in the number of biologics gaining regulatory approval each year. Biologics are defined…
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The Human Cell Atlas – an aid to understanding COVID-19 & a valuable tool in the development of hiPSC models
The outbreak of the novel viral disease, COVID-19, caused by the severe acute respiratory syndrome (SARS) coronavirus 2 (SARS-CoV-2), has led to worldwide health and economic catastrophe.1 Almost 2 million…
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