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Updates - Page 2

ADC, Antibody drug conjugate,
20th April, 2023

Antibody drug conjugates (ADCs) – the role of in vitro models in safety assessment

One the fastest growing approaches to treat cancer is the use of antibody drug conjugates (ADCs). Since the approval of the first antibody drug conjugate  in 2000,…

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13th April, 2023

The inside story of the development of Newcells’ MPS flow model: Scientific chat with Dr Colin Brown

When did you start thinking about incorporating flow into static kidney models? I have been working with static kidney models for over 30 years and started to think about…

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Newcells Biotech
21st March, 2023

Newcells Biotech collaborates with consortium in Eurostars funded project to advance novel therapy for Alpha-1 Antitrypsin (AAT) Deficiency

The Eurostars grant of €1.2m will support the partners, led by Gain, and includes Newcells, the Institute for Research in Biomedicine (Lausanne) and the University of Helsinki.  Newcells will…

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fibroblast and collagen
27th February, 2023

The latest FMT Assay: An invaluable tool for modelling fibrotic disease

Fibrotic diseases, including liver fibrosis, pulmonary fibrosis, and renal fibrosis, are characterized by the excessive deposition of extracellular matrix (ECM) components, leading to the formation of fibrous tissue that…

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aProximate™ Assay-Ready Plates launch poster.
18th January, 2023

New Product Launched – aProximate™ 96-well Assay-Ready Plates

Get our aProximate™ PTCs to your lab anywhere in the world (24 & 96-well plates) aProximate™ Assay-ready plates contain freshly isolated primary human proximal tubule cells (PTCs). The plates are…

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A cropped image of the Newcells team wearing festive jumpers
9th December, 2022

Newcells team support charity with festive jumpers

Thursday 8th December 2022 was Christmas Jumper Day in the UK to raise money for the charity Save the Children. A prize was given for the…

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Three men wearing matching t-shirts
24th November, 2022

NB staff supports Motor Neurone Disease Charity

Having become engaged (now married!) in the summer of 2021, Will’s thoughts turned to arrangements for his stag party. Rather than take the traditional route Will hatched a plan…

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A massively zoomed in image for the slider
12th October, 2022

First podocyte toxicity assay now commercially available

Damage to the glomerular filtration barrier (GFB) results in protein leakage from the plasma into the urine, so called proteinuria, and is associated with loss of kidney function, which…

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11th August, 2022

How a glomerulus in vitro model can accelerate drug development

The glomerulus is the part of the kidney involved in the filtration of solutes and waste from the blood. Damage to the glomerulus by diabetes mellitus, hypertension, glomerulonephritis, or…

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24 Plate Product
13th July, 2022

New Product Launched – aProximate™ Assay-Ready Plates for transporter studies

aProximate™ Assay-ready plates contain freshly isolated primary human proximal tubule cells (PTCs). The plates are provided in an easy to use 24-well Transwell® format. Visit our product page…

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Accelerate preclinical testing
15th June, 2022

Gene therapy vectors: Preclinical testing with retinal organoids

Adeno Associated Virus (AAV) vectors have emerged as the most successful retinal gene therapy vectors following the FDA approval of Luxturna in 2017. This new gene therapy product is…

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Organ on chip
31st May, 2022

Organ-on-a-chip: the next generation tool for drug development?

Organ-on-a-chip (OoC) or Microphysiological systems (MPS) are microfluidic devices providing a controlled microenvironment for miniaturised tissues mimicking physiological architecture and function of human tissues and organs. The application of dynamic…

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