Updates - Page 2
Pulmonary toxicity – a challenge for drug development
Despite the common assumption that adverse drug reactions usually affect the kidney and liver, over 600 medications have been reported to induce lung toxicity.1 Due to the large surface area,…
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ARVO Highlights
About the conference: ARVO The ARVO conference took place in the New Orleans Ernest N. Morial Convention Center. With over 10 000 attendees, the venue was absolutely huge. If you…
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Latest innovation in retina models brings a fully characterised Retina Pigment Epithelium (RPE)
Why develop an RPE model? Retinal pigment epithelium (RPE) cells play a vital role in the retina by forming the outer blood-retinal barrier and maintaining photoreceptor and visual…
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Antibody drug conjugates (ADCs) – the role of in vitro models in safety assessment
One the fastest growing approaches to treat cancer is the use of antibody drug conjugates (ADCs). Since the approval of the first antibody drug conjugate in 2000,…
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The inside story of the development of Newcells’ MPS flow model: Scientific chat with Dr Colin Brown
When did you start thinking about incorporating flow into static kidney models? I have been working with static kidney models for over 30 years and started to think about…
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Newcells Biotech collaborates with consortium in Eurostars funded project to advance novel therapy for Alpha-1 Antitrypsin (AAT) Deficiency
The Eurostars grant of €1.2m will support the partners, led by Gain, and includes Newcells, the Institute for Research in Biomedicine (Lausanne) and the University of Helsinki. Newcells will…
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The latest FMT Assay: An invaluable tool for modelling fibrotic disease
Fibrotic diseases, including liver fibrosis, pulmonary fibrosis, and renal fibrosis, are characterized by the excessive deposition of extracellular matrix (ECM) components, leading to the formation of fibrous tissue that…
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New Product Launched – aProximate™ 96-well Assay-Ready Plates
Get our aProximate™ PTCs to your lab anywhere in the world (24 & 96-well plates) aProximate™ Assay-ready plates contain freshly isolated primary human proximal tubule cells (PTCs). The plates are…
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Newcells team support charity with festive jumpers
Thursday 8th December 2022 was Christmas Jumper Day in the UK to raise money for the charity Save the Children. A prize was given for the…
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NB staff supports Motor Neurone Disease Charity
Having become engaged (now married!) in the summer of 2021, Will’s thoughts turned to arrangements for his stag party. Rather than take the traditional route Will hatched a plan…
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First podocyte toxicity assay now commercially available
Damage to the glomerular filtration barrier (GFB) results in protein leakage from the plasma into the urine, so called proteinuria, and is associated with loss of kidney function, which…
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How a glomerulus in vitro model can accelerate drug development
The glomerulus is the part of the kidney involved in the filtration of solutes and waste from the blood. Damage to the glomerulus by diabetes mellitus, hypertension, glomerulonephritis, or…
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