Latest Publication: Read our teams’ latest paper in Antibiotics, showing reduced nephrotoxicity of a novel formulation of polymyxin B compared to the clinical formulation using a validated primary human proximal tubule cell model.
Despite the common assumption that adverse drug reactions usually affect the kidney and liver, over 600 medications have been reported to induce lung toxicity.1 Due to the large surface area,…
Read update 5th May, 2023About the conference: ARVO The ARVO conference took place in the New Orleans Ernest N. Morial Convention Center. With over 10 000 attendees, the venue was absolutely huge. If you…
Read update 28th April, 2023Why develop an RPE model? Retinal pigment epithelium (RPE) cells play a vital role in the retina by forming the outer blood-retinal barrier and maintaining photoreceptor and visual…
Read update 20th April, 2023One the fastest growing approaches to treat cancer is the use of antibody drug conjugates (ADCs). Since the approval of the first antibody drug conjugate in 2000,…
Read update 13th April, 2023When did you start thinking about incorporating flow into static kidney models? I have been working with static kidney models for over 30 years and started to think about…
Read update 21st March, 2023The Eurostars grant of €1.2m will support the partners, led by Gain, and includes Newcells, the Institute for Research in Biomedicine (Lausanne) and the University of Helsinki. Newcells will…
Read update 27th February, 2023Fibrotic diseases, including liver fibrosis, pulmonary fibrosis, and renal fibrosis, are characterized by the excessive deposition of extracellular matrix (ECM) components, leading to the formation of fibrous tissue that…
Read update 18th January, 2023Get our aProximate™ PTCs to your lab anywhere in the world (24 & 96-well plates) aProximate™ Assay-ready plates contain freshly isolated primary human proximal tubule cells (PTCs). The plates are…
Read update 9th December, 2022Thursday 8th December 2022 was Christmas Jumper Day in the UK to raise money for the charity Save the Children. A prize was given for the…
Read update 24th November, 2022Having become engaged (now married!) in the summer of 2021, Will’s thoughts turned to arrangements for his stag party. Rather than take the traditional route Will hatched a plan…
Read update 12th October, 2022Damage to the glomerular filtration barrier (GFB) results in protein leakage from the plasma into the urine, so called proteinuria, and is associated with loss of kidney function, which…
Read update 11th August, 2022The glomerulus is the part of the kidney involved in the filtration of solutes and waste from the blood. Damage to the glomerulus by diabetes mellitus, hypertension, glomerulonephritis, or…
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