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Scientific Publications
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Development of a novel predictive in vitro non human primate proximal tubule model for drug transporter & nephrotoxicity studies
Colin Brown Drug Metabolism and Pharmacokinetics. 2019; 34(1):S53
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In vitro models for accurate prediction of renal tubular xenobiotic transport in vivo
Jelle Vriend, Keith R. Pye, Colin Brown. Current Opinion in Toxicology. 2021; 25: 15-22
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Freshly isolated primary human proximal tubule cells as an in vitro model for the detection of renal tubular toxicity
Piyush Bajaj, Git Chung, Keith Pye, Tomoya Yukawa, Akio Imanishi, Yuichi Takai, Colin Brown, Matthew P.Wagoner
Toxicology. 2020; 442:152535
Posters
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A predictive in vitro primary proximal tubule platform for derisking of antibiotic-induced kidney injury
A Sensitive Nephrotoxicity Assay of in vitro Podocyte Effacement
A Live Cell High Content Imaging Assay for Monitoring Large Molecules Uptake into aProximateTM Proximal Tubule Epithelial Cells via Megalin and Cubulin
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Scientific eBooks and Protocols
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Case Studies
View allQuantitative Fibroblast-to-Myofibroblast Transition (FMT) studies
Quantitative FMT assay with high content imaging
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In vitro evaluation of ocular toxicity and phenotypic rescue
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In vitro selection of the most relevant species to predict human
Evaluation of glomerular ADC toxicity in podocytes
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Gene therapy viral vector assessment on retinal organoids
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Gene therapy viral vector assessment on RPE cells
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