The results of a recent collaboration between Sanofi, GSK, Lilly, Vesalius Therapeutics, Leiden University, Heidelberg University, ElmorePathology and Newcells aimed at enhancing safety assessments has just been published. Find out how rat kidney gene co-expression networks has enabled biomarker identification and human translation for renal safety assessments.
A Primary Human in vitro Focal Segmental Glomerulosclerosis (FSGS) model for drug development applications
An in vitro Human Primary Thick Ascending Limb Model For The Assessment of Compound Nephrotoxicity
A predictive in vitro primary proximal tubule platform for derisking of antibiotic-induced kidney injury
Overcoming technical difficulties of in vitro assay – development
A Sensitive Nephrotoxicity Assay of in vitro Podocyte Effacement
A Live Cell High Content Imaging Assay for Monitoring Large Molecules Uptake into aProximateTM Proximal Tubule Epithelial Cells via Megalin and Cubulin
Development of highly-differentiated human primary proximal tubule MPS model (aProximate MPS™ Flow)
The aProximate™ in vitro renal proximal tubule cell model as a platform to investigate the renal uptake and nephrotoxic liability of Antisense Oligonucleotide drug molecules
An in-vitro high-content imaging assay for the study of fibroblast activation and matrix deposition