Skip to content
Announcement:

Our latest paper in collaboration with Pfizer on the role of OCT2/MATE in creatinine clearance is accepted in JPET.

Updates: Update

29th August, 2023

Latest Advances in CAR-T Therapy with novel HLA-typed in vitro cell tools

CAR-T Therapy CAR-T Therapy is a form of immunotherapy that harnesses the power of the patient’s immune system to target and eliminate cancer cells. It involves ex-vivo genetic engineering of…

Read update
28th July, 2023

MPS summit highlights

About the conference: MPS summit The MPS summit is a small but buzzing conference, where scientists from the pharma industry, academia and microchip manufacturers gather to discuss the latest advances…

Read update
Accelerate preclinical testing
15th June, 2022

Gene therapy vectors: Preclinical testing with retinal organoids

Adeno Associated Virus (AAV) vectors have emerged as the most successful retinal gene therapy vectors following the FDA approval of Luxturna in 2017. This new gene therapy product is…

Read update
Organ on chip
31st May, 2022

Organ-on-a-chip: the next generation tool for drug development?

Organ-on-a-chip (OoC) or Microphysiological systems (MPS) are microfluidic devices providing a controlled microenvironment for miniaturised tissues mimicking physiological architecture and function of human tissues and organs. The application of dynamic…

Read update
Glomerulus surrounded by convoluted tubules
11th March, 2022

Why is an in vitro model of the glomerulus desperately needed?

In most cases, once the kidney’s function is limited, the only treatment options are dialysis and kidney transplant. The absence of effective drugs to treat kidney disease is partly…

Read update
How to reduce drug attrition during drug development
1st February, 2022

How to reduce drug attrition during drug development?

There are two main causes of drug attrition: safety and efficacy, and in both instances, the common denominator is the inadequacy of current preclinical models to predict outcomes in…

Read update
28th July, 2023

MPS summit highlights

About the conference: MPS summit The MPS summit is a small but buzzing conference, where scientists from the pharma industry, academia and microchip manufacturers gather to discuss the latest advances…

Read update
30th June, 2023

3rd ILD Summit Highlights

About the conference : ILD Summit The ILD Summit is a niche industry dedicated conference focussed on advancing therapies for progressive fibrosing interstitial lung diseases (ILD). This year’s conference was the…

Read update
Pulmonary toxicity – a challenge for drug and chemical development
16th June, 2023

Pulmonary toxicity – a challenge for drug development

Despite the common assumption that adverse drug reactions usually affect the kidney and liver, over 600 medications have been reported to induce lung toxicity.1 Due to ehri large surface area,…

Read update
5th May, 2023

ARVO Highlights

About the conference: ARVO The ARVO conference took place in the New Orleans Ernest N. Morial Convention Center.  With over 10 000 attendees, the venue was absolutely huge. If you…

Read update
iPSC-derived retinal pigment epithelial (RPE) cells
28th April, 2023

Latest innovation in retina models brings a fully characterised Retina Pigment Epithelium (RPE)

Why develop an RPE model? Retinal pigment epithelium (RPE) cells play a vital role in the retina by forming the outer blood-retinal barrier and maintaining photoreceptor and visual…

Read update
ADC, Antibody drug conjugate,
20th April, 2023

Antibody drug conjugates (ADCs) – the role of in vitro models in safety assessment

One the fastest growing approaches to treat cancer is the use of antibody drug conjugates (ADCs). Since the approval of the first antibody drug conjugate  in 2000,…

Read update

Get our latest updates straight to your inbox